Angina Research Today is a free monthly online journal that collates and summarizes the latest research about Angina, including details on symptoms, treatment, causes, prevention, surgery. | ||||||||
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The value of magnetocardiography in the course of coronary intervention.Hailer B, Van Leeuwen P, Chaikovsky I, Auth-Eisernitz S, Schäfer H, Grönemeyer D Department of Medicine, Philippusstift, Essen, Germany. b.hailer@philippusstift.de BACKGROUND: The noninvasive detection of restenosis after percutaneous coronary intervention (PCI) remains a clinical challenge. Previous studies have shown that magnetocardiograms reveal obvious changes in patients with coronary artery disease (CAD) and normal electrocardiogram (ECG) at rest. HYPOTHESIS: The present study aimed to evaluate the potential of magnetocardiography (MCG) for the detection of electrophysiological changes in the course of successful PCI. METHODS: Twelve-lead ECG and unshielded four-channel MCG (SQUID AG, Essen, Germany) were registered at nine prethoracic sites in 50 patients with CAD (62 +/- 10 years; EF = 76 +/- 11%; registration: before, 24 hours, and 1 month (n = 25) after PCI) and 57 normals (51 +/- 9 years). Current density vector (CDV) maps were reconstructed within the ST-T interval and classified from category 0 (normal) to category 4 (grossly abnormal). In both groups and at all registration times, the percentage of each category of maps was calculated and compared. RESULTS: Most CDV maps of normals were classified as category 0, 1, or 2 compared to CAD patients before PCI with most maps of category 3 and 4 (P < 0.0005). Twenty-four hours after PCI, more maps were classified as category 2 (P < 0.05) and less as category 4 (P < 0.005). One month after PCI the MCG results further improved: more maps were classified as category 1 (P < 0.05) and 2 (P < 0.005) and less maps as category 4 (P < 0.0001). The ECG remained unchanged in the course of PCI. CONCLUSION: Unshielded four-channel MCG reveals obvious changes in the course of successful PCI on the basis of CDV map reconstruction during repolarization. The method seems to be suitable for the follow-up of patients after PCI. Published 21 April 2005 in Ann Noninvasive Electrocardiol, 10(2): 188-96.
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