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Relation of anemia at discharge to survival after acute coronary syndromes.

Vaglio J, Safley DM, Rahman M, Kosiborod M, Jones P, Thompson R, Krumholz HM, Spertus JA

Mid America Heart Institute of Saint Luke's Hospital, Missouri, USA.

Two-year survival rate was assessed among 1,038 patients who had acute coronary syndromes that were classified by discharge hematocrit values as normal (>39%, n = 360, 34.7%), mildly anemic (33.1% to 39%, n = 430, 41.4%), or moderately/severely anemic (< or = 33%, n = 248, 23.9%). Worsening anemia was associated with a decreased 2-year survival rate (normal 95.8%, mild anemia 91.2%, moderate/severe anemia 81.5%, p < 0.001). In multivariable analyses, adjusted hazard ratios for all-cause mortality were 1.57 (95% confidence interval 0.82 to 2.96) for mild anemia and 2.46 (95% confidence interval 1.25 to 4.85) for moderate/severe anemia.

Published 15 August 2005 in Am J Cardiol, 96(4): 496-9.
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